Applying solitary-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our study pursuits include things like:
You regularly become involved in discussions about science and religion. You've also penned many books on the topic. Don’t you believe that in some unspecified time in the future We are going to know every thing Which God’s part will be in excess of?
[Laughs] ‘It was certainly a terrific threat! At time, I was nicely aware that it could go wrong Which I could come to be significantly less profitable, but I just dismissed that. Curiosity has often been my strongest driving pressure. And fortuitously it all labored out.’
2007, initially real-time detection of strand exchange in homologous recombination by RecA; discovery of the low persistence size of finishes of microtubules; and fixed the mechanism of biosensing with carbon nanotubes
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The coiled-coil of the human Rad50 DNA repair service protein includes specific segments of greater versatility
MATLAB codes for data processing are offered at . Julia codes utilized for numerical simulation are available at .
Atomic drive microscopy shows that vaccinia topoisomerase IB generates filaments on DNA within a cooperative trend
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Resolving the phase measurement in condensin-driven DNA loop extrusion identifies ATP binding since the stage-producing method
An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes
Quite a few new phenomena were being identified, and he and his study group established a leading posture Within this field of exploration. Dekker and his exploration group found new physics of nanotubes and explored the feasibility of molecular electronics. In 1998, they have been the first to create a transistor according to one nanotube molecule.
By way of example, we consider the nucleopore complicated, a gateway between the mobile nucleus as well as the cytoplasm. This is a very sophisticated process and so hard to analyze in the cell, so we use biomimetics. We reconstruct holes and then insert particular person factors of the nucleopore elaborate to review transport as a result of it at The only-molecule amount.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in ceesdekker.net de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent style and design in 2005. (nl)